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Scientists have created a unique map of England and Wales that reveals detailed variations in the use of a single medicine. The drug is sodium valproate, a treatment for severe cases of epilepsy that is also known to

cause health problems for pregnant women

.

The findings show …

A secretive group that donated £130,000 to Labour and claimed to be “merely a platform for people” is in fact funded by property developers, the

Observer

can reveal.

The firm behind a £200m project to build a skyscraper in Birmingham and three other developers are behind the West Midlands …

First, a simple stat: Bristol notched a 10th consecutive away win in the Premiership. A new record for the league. Impressive. Second, another: they scored the most points any team have ever registered against Leicester at Welford Road, as much as any have ever scored against the Tigers anywhere in …

Just 2% or fewer of trains on some of the busiest Avanti West Coast services between London and Manchester are leaving and arriving on time, analysis of National Rail figures reveals.

The operator of West Coast Main Line services remains the worst rail company in the UK for delays despite …

When Jorge Rivera-Herrans released part of

Epic: the Musical

last Christmas, he managed to push Taylor Swift off the top of the US iTunes album charts. So there is a lot at stake when the final instalment of his musical retelling of the Odyssey is released on Christmas Day.

At least 22 people have been killed in a “tragic” traffic collision between a bus and truck in the Brazilian state of Minas Gerais, the Associated Press reports, citing fire department officials who attended the scene.

A further 13 people were taken to hospitals near the city of Teófilo Otoni.

The building of a controversial 25-storey office block nicknamed the Slab on London’s South Bank is to go ahead after the high court upheld a decision by the former communities secretary Michael Gove to approve the development.

Mr Justice Mould dismissed a legal challenge by the Save Our South Bank …

Baron Edmond de Rothschild was one of Europe’s richest and best connected men. But his lifelong hobby – hunting the autographs of the famous – was more akin to that of an idolising youngster.

Nine decades after his death, more than 220 letters he collected over 60 years have just …

Crambo, dismissed in the betting at 9-1 despite his narrow win in the Long Walk Hurdle 12 months ago, returned to Ascot for the first time since and rediscovered his form in impressive fashion here on Saturday, edging home by a head from Hiddenvalley Lake and briefly reducing Fergal O’Brien, …

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